Annotation Overview for fig|279808.3.peg.2461 in Staphylococcus haemolyticus JCSC1435:
Prephenate dehydrogenase (EC 1.3.1.12)

current assignment	Prephenate dehydrogenase (EC 1.3.1.12)	EC Number	1.3.1.12
taxonomy id	279808	contig	279808.3:NC_007168 (2,685,016bp)279808.3:NC_007169 (2,301bp)279808.3:NC_007170 (2,367bp)279808.3:NC_007171 (8,181bp)
internal links	genome browser | feature evidence | sequence	ACH Annotation Clearinghouse (ACH) The Annotation Clearinghouse offers a mapping of genes which are identical in sequence except for the start region (due to differences in start calling). [?]	show essentially identical genes
annotation history		run tool	Psi-BlastTMpredTMHMMGram negative PSORTGram negative SignalPGram positive PSORTGram positive SignalPLipoPInterProScanRadarPPSearchGram negative CELLOGram positive CELLOProDomPDB
FigFam	FIG134297	comment	TyrAp/ACT domain, NAD-specific
data base cross references (dbxref)	NCBI: 68447269 RefSeq: YP_253459.1 NCBI: 70726545 UniProt: TYRA_STAHJ NCBI: 123660149 UniProt: Q4L672 CMR: NTL01SH1544

Annotation History (history of similar genes)

Date	Annotator	Annotation
9/28/2005	ncbi	Set FIG function to prephenate dehydrogenase
10/7/2005	automated_assignments	Set FIG function to Prephenate dehydrogenase (EC 1.3.1.12)
8/8/2007	master:carolb	Assigning function Prephenate dehydrogenase (EC 1.3.1.12) # NAD-specific, ACT domain based on installation of subsystem Phenylalanine_and_Tyrosine_Branches
8/8/2007	carolb	Set FIG function to Prephenate dehydrogenase (EC 1.3.1.12) # NAD-specific, ACT domain
10/1/2008	carolb	Set FIG function to Prephenate dehydrogenase (EC 1.3.1.12) # TyrAp/ACT domain, NAD-specific
10/1/2008	carolb	Set FIG function to Prephenate dehydrogenase (EC 1.3.1.12) # TyrAp/ACT domain, NAD-specific

We have assigned the function "Prephenate dehydrogenase (EC 1.3.1.12) # TyrAp/ACT domain, NAD-specific" to the encoded protein. The protein occurs in 2 subsystems: "Chorismate Synthesis", and "Phenylalanine and Tyrosine Branches from Chorismate". In "Chorismate Synthesis", it appears to play a functional role that we have not associated with any other gene. In "Phenylalanine and Tyrosine Branches from Chorismate", it appears to play a functional role that we have not associated with any other gene.

The chromosomal region of the focus gene (top) is compared with four similar organisms. The graphic is centered on the focus gene, which is red and numbered 1. Sets of genes with similar sequence are grouped with the same number and color. Genes whose relative position is conserved in at least four other species are functionally coupled and share gray background boxes. The size of the region and the number of genomes may be reset. Click on any arrow in the display to refocus the comparison on that gene. The focus gene always points to the right, even if it is located on the minus strand.